The pneumotaxic center, also known as the pontine respiratory group (PRG), is a network of neurons in the rostral dorsal lateral pons. It consists of the Kölliker-Fuse nucleus and the medial parabrachial nucleus.

The PRG antagonises the apneustic center, cyclically inhibiting inspiration. The PRG limits the burst of action potentials in the phrenic nerve, effectively decreasing the tidal volume and regulating the respiratory rate. Absence of the PRG results in an increase in depth of respiration and a decrease in respiratory rate.